Laboratory of Chemical Life Science

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DNA, RNA, and proteins are the basic molecular building blocks of life, but the living cell contains additional molecules, including water, ions, small chemical compounds, glycans, lipids, and other biochemical molecules, without which the cell would not function. Because the proteins responsible for biosynthesis, biodegradation, and transport of these additional molecules are encoded in the genome, one may assert that all cellular functions are specified by the genomic DNA sequence. In practice, however, it is not possible to infer higher-level systemic functions of the cell or the organism simply from the molecular sequence infomation alone. We are developing bioinformatics methods to integrate different types of data and knowledge on various aspects of the biological systems towards basic understanding of life as a molecular interaction/reaction system and also for practical applications in medical and pharmaceutical sciences.
Bioinformatics Center Institute for Chemical Research Kyoto University